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FAVITES (FrAmework for VIral Transmission and Evolution Simulation) is a robust modular framework for the simultaneous simulation of a transmission network and viral evolution, as well as simulation of sampling imperfections of the transmission network and of the sequencing process. The framework is robust in that the simulation process has been broken down into a series of interactions between abstract module classes, and the user can simply plug in each desired module implementation (or implement one from scratch) to customize any stage of the simulation process.

Contents

• Installation
• Usage
• Output Folder Structure
• Designing a Configuration File
• Post-Validation
• Helper Scripts
• General Workflow
• File Formats
• Modules
• Development Guide