diff --git a/.github/test-spec.yml b/.github/test-spec.yml
new file mode 100644
index 00000000000..7f896b3c58f
--- /dev/null
+++ b/.github/test-spec.yml
@@ -0,0 +1,312 @@
+# This is the Jenkins ci variant of the .github/labler.yaml
+
+"CI-run-zephyr-twister":
+  - any:
+      - "!.github/**/*"
+      - "!doc/**/*"
+      - "!CODEOWNERS"
+      - "!LICENSE"
+      - "!**/*.rst"
+      - "!VERSION"
+      - "!submanifests/**/*"
+      - "!MAINTAINERS.yml"
+      - "!version.h.in"
+      - "!Jenkinsfile"
+      - "!**/*.md"
+
+"CI-iot-zephyr-lwm2m-test":
+  - "drivers/console/**/*"
+  - "drivers/flash/**/*"
+  - "subsys/dfu/boot/**/*"
+  - "subsys/net/ip/**/*"
+  - "subsys/net/lib/http/**/*"
+  - "subsys/net/lib/lwm2m//**/*"
+  - "subsys/net/**/*"
+
+"CI-iot-samples-test":
+  - "boards/nordic/nrf9160dk/**/*"
+  - "dts/arm/nordic/nrf9160*"
+  - "include/net/**/*"
+  - "subsys/net/lib/**/*"
+
+"CI-iot-libraries-test":
+  - "boards/nordic/nrf9160dk/**/*"
+  - "dts/arm/nordic/nrf9160*"
+  - "include/net/socket_ncs.h"
+  - "subsys/testsuite/ztest/**/*"
+
+"CI-lwm2m-test": null
+# Not necessary to run tests on changes to this repo.
+
+"CI-boot-dfu-test":
+  - "subsys/mgmt/mcumgr/**/*"
+  - "subsys/dfu/**/*"
+  - "include/mgmt/mcumgr/**/*"
+  - "include/dfu/**/*"
+  - "samples/subsys/mgmt/mcumgr/smp_svr/**/*"
+
+"CI-tfm-test":
+  - "boards/nordic/nrf5340dk/**/*"
+  - "boards/nordic/nrf9160dk/**/*"
+  - "drivers/entropy/*"
+  - "dts/arm/nordic/nrf5340*"
+  - "dts/arm/nordic/nrf9160*"
+  - "modules/trusted-firmware-m/**/*"
+  - "samples/tfm_integration/**/*"
+
+"CI-ble-test":
+  - any:
+      - "drivers/bluetooth/**/*"
+  - any:
+      - "dts/arm/nordic/nrf5*"
+  - any:
+      - "subsys/bluetooth/**/*"
+      - "!subsys/bluetooth/mesh/**/*"
+      - "!subsys/bluetooth/audio/**/*"
+  - any:
+      - "include/zephyr/bluetooth/**/*"
+      - "!include/zephyr/bluetooth/mesh/**/*"
+  - "samples/bluetooth/hci_rpc/**/*"
+
+"CI-ble-samples-test":
+  - any:
+      - "drivers/bluetooth/**/*"
+  - any:
+      - "dts/arm/nordic/nrf5*"
+  - any:
+      - "subsys/bluetooth/**/*"
+      - "!subsys/bluetooth/mesh/**/*"
+      - "!subsys/bluetooth/audio/**/*"
+  - any:
+      - "include/zephyr/bluetooth/**/*"
+      - "!include/zephyr/bluetooth/mesh/**/*"
+  - "samples/bluetooth/**/*"
+
+"CI-mesh-test":
+  - "subsys/bluetooth/mesh/**/*"
+  - "include/zephyr/bluetooth/mesh/**/*"
+  - "samples/bluetooth/mesh/**/*"
+  - "samples/bluetooth/mesh_demo/**/*"
+  - "samples/bluetooth/mesh_provisioner/**/*"
+  - "tests/bluetooth/mesh/**/*"
+  - "tests/bluetooth/mesh_shell/**/*"
+
+"CI-zigbee-test":
+  - "subsys/mgmt/mcumgr/**/*"
+  - "subsys/dfu/**/*"
+  - "include/mgmt/mcumgr/**/*"
+  - "include/dfu/**/*"
+
+"CI-thingy91-test":
+  - "boards/nordic/nrf9160dk/**/*"
+  - "arch/x86/core/**/*"
+  - "arch/x86/include/**/*"
+  - "drivers/console/**/*"
+  - "drivers/ethernet/**/*"
+  - "drivers/flash/**/*"
+  - "drivers/hwinfo/**/*"
+  - "drivers/interrupt_controller/**/*"
+  - "drivers/net/**/*"
+  - "drivers/serial/**/*"
+  - "drivers/timer/**/*"
+  - "include/**/*"
+  - "kernel/**/*"
+  - "lib/libc/common/source/stdlib/**/*"
+  - "lib/libc/newlib/**/*"
+  - "lib/libc/picolibc/**/*"
+  - "lib/os/**/*"
+  - "lib/posix/**/*"
+  - "misc/**/*"
+  - "modules/mbedtls/**/*"
+  - "soc/x86/ia32/**/*"
+  - "subsys/fs/fcb/**/*"
+  - "subsys/logging/**/*"
+  - "subsys/net/**/*"
+  - "subsys/random/**/*"
+  - "subsys/settings/include/**/*"
+  - "subsys/settings/src/**/*"
+  - "subsys/stats/**/*"
+  - "subsys/storage/flash_map/**/*"
+  - "subsys/storage/stream/**/*"
+  - "subsys/tracing/**/*"
+
+"CI-desktop-test":
+  - any:
+      - "**/*"
+      - "!samples/bluetooth/**/*"
+      - "!tests/bluetooth/**/*"
+
+"CI-crypto-test":
+  - "boards/nordic/nrf52840dk/**/*"
+  - "boards/nordic/nrf5340dk/**/*"
+  - "boards/nordic/nrf9160dk/**/*"
+  - "drivers/entropy/*"
+  - "drivers/serial/**/*"
+  - "dts/arm/nordic/nrf52840*"
+  - "dts/arm/nordic/nrf5340*"
+  - "dts/arm/nordic/nrf9160*"
+  - "include/drivers/serial/**/*"
+  - "modules/mbedtls/**/*"
+
+"CI-fem-test":
+  - any:
+      - "**/*"
+      - "!samples/bluetooth/**/*"
+      - "!tests/bluetooth/**/*"
+
+"CI-rs-test":
+  - any:
+      - "**/*"
+      - "!samples/bluetooth/**/*"
+      - "!tests/bluetooth/**/*"
+
+"CI-thread-test":
+  - "include/zephyr/net/**/*"
+  - "modules/mbedtls/**/*"
+  - "modules/openthread/**/*"
+  - "samples/net/openthread/**/*"
+  - "soc/arm/nordic_nrf/**/*"
+  - "subsys/net/**/*"
+  - "subsys/settings/**/*"
+
+"CI-nfc-test":
+  - any:
+      - "**/*"
+      - "!samples/bluetooth/**/*"
+      - "!tests/bluetooth/**/*"
+
+"CI-matter-test":
+  - "include/dfu/**/*"
+  - "include/mgmt/mcumgr/**/*"
+  - "soc/arm/nordic_nrf/**/*"
+  - "subsys/dfu/**/*"
+  - "subsys/settings/**/*"
+  - "subsys/net/**/*"
+  - "subsys/mgmt/mcumgr/**/*"
+  - "drivers/net/**/*"
+  - "samples/bluetooth/hci_rpc/**/*"
+  - any:
+      - "subsys/bluetooth/**/*"
+      - "!subsys/bluetooth/mesh/**/*"
+      - "!subsys/bluetooth/audio/**/*"
+
+"CI-find-my-test":
+  - any:
+      - "**/*"
+      - "!samples/bluetooth/**/*"
+      - "!tests/bluetooth/**/*"
+
+"CI-gazell-test":
+  - any:
+      - "**/*"
+      - "!samples/bluetooth/**/*"
+      - "!tests/bluetooth/**/*"
+
+"CI-rpc-test":
+  - any:
+      - "**/*"
+      - "!samples/bluetooth/**/*"
+      - "!tests/bluetooth/**/*"
+
+"CI-modemshell-test":
+  - "include/net/**/*"
+  - "include/posix/**/*"
+  - "include/shell/**/*"
+  - "drivers/net/**/*"
+  - "drivers/serial/**/*"
+  - "drivers/wifi/**/*"
+  - "subsys/shell/**/*"
+  - "subsys/net/**/*"
+  - "subsys/settings/**/*"
+
+"CI-positioning-test":
+  - "include/net/**/*"
+  - "include/posix/**/*"
+  - "drivers/net/**/*"
+  - "drivers/wifi/**/*"
+  - "subsys/net/**/*"
+  - "subsys/settings/**/*"
+
+"CI-cloud-test":
+  - "include/zephyr/dfu/**/*"
+  - "include/zephyr/net/**/*"
+  - "include/zephyr/posix/**/*"
+  - "include/zephyr/settings/**/*"
+  - "drivers/led/**/*"
+  - "drivers/net/**/*"
+  - "drivers/sensor/**/*"
+  - "drivers/serial/**/*"
+  - "drivers/wifi/**/*"
+  - "lib/posix/**/*"
+  - "soc/arm/nordic_nrf/**/*"
+  - "subsys/dfu/**/*"
+  - "subsys/net/**/*"
+  - "subsys/settings/**/*"
+
+"CI-wifi":
+  - "subsys/net/l2/wifi/**/*"
+  - "subsys/net/l2/ethernet/**/*"
+
+"CI-sidewalk-test":
+  - "include/dfu/**/*"
+  - "include/mgmt/mcumgr/**/*"
+  - "soc/arm/nordic_nrf/**/*"
+  - "subsys/dfu/**/*"
+  - "subsys/settings/**/*"
+  - "subsys/mgmt/mcumgr/**/*"
+  - "samples/bluetooth/hci_rpc/**/*"
+  - any:
+      - "subsys/bluetooth/**/*"
+      - "!subsys/bluetooth/mesh/**/*"
+      - "!subsys/bluetooth/audio/**/*"
+
+"CI-audio-test":
+  - "boards/nordic/nrf5340_audio_dk/**/*"
+  - "drivers/flash/**/*"
+  - "drivers/spi/**/*"
+  - "drivers/gpio/**/*"
+  - "drivers/i2c/**/*"
+  - "drivers/watchdog/**/*"
+  - "include/dfu/**/*"
+  - "include/mgmt/mcumgr/**/*"
+  - "samples/bluetooth/hci_rpc/**/*"
+  - "soc/arm/nordic_nrf/**/*"
+  - "subsys/bluetooth/audio/**/*"
+  - "subsys/bluetooth/host/**/*"
+  - "subsys/dfu/**/*"
+  - "subsys/fs/**/*"
+  - "subsys/mgmt/mcumgr/**/*"
+  - "subsys/sd/**/*"
+  - "subsys/storage/**/*"
+  - "subsys/task_wdt/**/*"
+  - "subsys/usb/**/*"
+  - "subsys/zbus/**/*"
+
+"CI-pmic-samples-test":
+  - "samples/shields/npm1300_ek/**/*"
+  - "boards/shields/npm1300_ek/**/*"
+  - "**/**npm1300**/**"
+  - "drivers/regulator/regulator_common.c"
+  - "drivers/regulator/regulator_shell.c"
+  - "drivers/gpio/gpio_shell.c"
+  - "drivers/sensor/sensor_shell.c"
+
+"CI-test-low-level":
+  - "dts/**/*"
+  - "boards/nordic/nrf54*/**/*"
+  - "include/zephyr/**/*"
+  - "tests/arch/**/*"
+  - "arch/**/*"
+  - "tests/kernel/**/*"
+  - "kernel/**/*"
+  - "tests/drivers/**/*"
+  - "drivers/**/*"
+  - "samples/subsys/settings/**/*"
+  - "subsys/settings/**/*"
+  - "samples/subsys/logging/**/*"
+  - "subsys/logging/**/*"
+  - "samples/sensor/**/*"
+  - "samples/hello_world/**/*"
+  - "samples/synchronization/**/*"
+  - "samples/drivers/watchdog/**/*"
+  - "modules/hal_nordic/**/*"
diff --git a/CODEOWNERS b/CODEOWNERS
index 60ce1a2533a..84faf677d91 100644
--- a/CODEOWNERS
+++ b/CODEOWNERS
@@ -18,6 +18,7 @@
 # component or code. This file is going to be deprecated and currently only had
 # entries that are not covered by the MAINTAINERS file.
 
+/.github/test-spec.yml                    @nrfconnect/ncs-test-leads
 /soc/arm/aspeed/                          @aspeeddylan
 /soc/atmel/                               @nandojve
 /soc/arm/bcm*/                            @sbranden