Add gene silencing assay

obi-ontology · Feb 7, 2024 · 1713178 · 1713178
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diff --git a/src/ontology/modules/assays.owl b/src/ontology/modules/assays.owl
@@ -26567,6 +26567,20 @@
 
 
 
+    <!-- http://purl.obolibrary.org/obo/OBI_0003658 -->
+
+    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003658">
+        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
+        <obo:IAO_0000111>gene silencing assay</obo:IAO_0000111>
+        <obo:IAO_0000115>An assay that is performed on material subject to gene silencing.</obo:IAO_0000115>
+        <obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
+        <obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/559</obo:IAO_0000233>
+        <obo:IAO_0000234>Philippe Rocca-Serra</obo:IAO_0000234>
+        <rdfs:label>gene silencing assay</rdfs:label>
+    </owl:Class>
+
+
+
     <!-- http://purl.obolibrary.org/obo/OBI_0100016 -->
 
     <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100016"/>

diff --git a/src/ontology/templates/assays.tsv b/src/ontology/templates/assays.tsv
@@ -656,6 +656,7 @@ OBI:0003599	single cell T cell receptor repertoire sequencing assay	single cell
 OBI:0003601	quartz crystal microbalance assay	quartz crystal microbalance assay		QCM	An assay that measures the change in frequency of a quartz crystal resonator resulting from the addition or removal of a small mass of a ligand specifically binding at the surface of the resonator.	http://www.ncbi.nlm.nih.gov/pubmed/23504432|https://en.wikipedia.org/wiki/Quartz_crystal_microbalance		Randi Vita|Bjoern Peters|Sebastian Duesing					subclass		assay														
 OBI:0003604	multiplexed error-robust fluorescence in situ hybridization assay			MERFISH	A fluorescence in-situ hybridization assay that uses combinatorial FISH labeling with error resistant encoding schemes for highly multiplexed single-molecule imaging.	https://en.wikipedia.org/wiki/Fluorescence_in_situ_hybridization#MERFISH		Sebastian Duesing			Brain Image Library	https://github.com/obi-ontology/obi/issues/1724	subclass		fluorescence in-situ hybridization assay														
 OBI:0003605	single molecule fluorescence in situ hybridization			smFISH	A fluorescence in-situ hybridization assay that detects single RNA molecules in fixed cells, allowing for both the quantification and localization at the single-cell level and single-molecule resolution.	https://doi.org/10.21769/BioProtoc.3070		Sebastian Duesing			Brain Image Library	https://github.com/obi-ontology/obi/issues/1725	subclass		fluorescence in-situ hybridization assay														
+OBI:0003658	gene silencing assay	gene silencing assay			An assay that is performed on material subject to gene silencing.			Sebastian Duesing			Philippe Rocca-Serra	https://github.com/obi-ontology/obi/issues/559	subclass		assay														
 OBI:0302736	comet assay		ready for release	single cell gel electrophoresis assay|SCGE assay	An assay that measures DNA damage (DNA breakage) in eucaryotic cells exposed to a challenge by determining the size and shape of DNA migration by detecting fluorescently labeled DNA from a cell placed in an electric field using gel electrophoresis	PMID:7686265	PMID: 18326531.Mutagenesis. 2008 Mar 6.Recommendations for design of the rat comet assay.	Philippe Rocca-Serra					subclass		assay		fluorescence microscopy assay	cell				('material entity' and ('has role' some 'dye role') and ('bearer of' some fluorescence))		agarose gel	information content entity	cellular response to DNA damage stimulus			
 OBI:0302737	PCR-SSCP assay		ready for release	polymerase chain reaction-single strand conformation polymorphism assay	An assay that identifies DNA sequence variation (mutation, deletion, insertions) in target DNA sequences amplified using polymerase chain reaction using gel electrophoresis and denaturating conditions	PMID:18219595	PMID: 17334176.Hum Exp Toxicol. 2007 Jan;26(1):9-18.Is there a role for PCR-SSCP among the methods for missense mutation detection of TP53 gene?	Philippe Rocca-Serra					subclass		genotyping assay	polymerase chain reaction|material component separation								amplified DNA	(image and 'genotype information')				
 OBI:0600002	tumor grading		pending final vetting	grading of tumor	An assay that determines the grade (severity/stage) of a tumor sample, used in cancer biology to describe abnormalities/qualities of tumor cells or tissues. Values can be described by terms from NCI Thesaurus.	OBI branch derived; submitted by MO		Compiled by Helen Parkinson for Transcriptomics thanks to Adam Witney					subclass		assay									specimen		disease course