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okadalabipr · Nov 22, 2023 · dabd57c · dabd57c
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 # Haga2023
 **Highlights**
 - Multi-omics analysis identified TGF-β1–SMAD4 as key regulators in human skin aging
-- THBS1 and FMOD promoted and suppressed factors in skin aging, respectively
-- THBS1 controlled the senescent and non-senescent states of the aging switch
+- THBS1 promoted and FMOD suppressed factors in skin aging
+- THBS1 controlled senescent and non-senescent state of the aging switch
 - SMAD4 is a potential target for inhibiting THBS1 expression and cell senescence
 
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