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comparing and filtering RNA structures in dot-bracket notation at equivalent sites between sequences

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A Lua script wrapped around the Crumple program (see, https://www.ncbi.nlm.nih.gov/pubmed/27665589) allowing for generation and filtering of all possible RNA structures in a given sequence, and pairwise comparison between a group of sequences to look for conservation. Resulting conserved structures are plotted in R.

Used in publication:

Limits of variation, specific infectivity, and genome packaging of massively recoded poliovirus genomes. https://www.ncbi.nlm.nih.gov/pubmed/28973853 PMID: 28973853 PMC: PMC5642728 DOI: 10.1073/pnas.1714385114

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comparing and filtering RNA structures in dot-bracket notation at equivalent sites between sequences

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