diff --git a/bioframe/io/resources.py b/bioframe/io/resources.py
index f7108c7b..ea60e7b2 100644
--- a/bioframe/io/resources.py
+++ b/bioframe/io/resources.py
@@ -246,7 +246,7 @@ def fetch_centromeres(db: str, provider: str = "local") -> pd.DataFrame:
 
 
 class UCSCClient:
-    BASE_URL = "http://hgdownload.cse.ucsc.edu/"
+    BASE_URL = "https://hgdownload.soe.ucsc.edu/"
 
     def __init__(self, db: str):
         self._db = db