Merge pull request #74 from pharmaverse/4_vx_test_data

Closes #4 Add vaccines test data
pharmaverse · Oct 19, 2023 · b106d41 · b106d41
2 parents 311be20 + a861424
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diff --git a/.github/workflows/common.yml b/.github/workflows/common.yml
@@ -15,14 +15,12 @@ on:
       - "v*"
     branches:
       - main
-      - devel
       - patch
   # 'pull_request' events are triggered when PRs are
   # created against one of these target branches.
   pull_request:
     branches:
       - main
-      - devel
       - patch
   # 'release' events are triggered when...
   # you guessed it - when releases are made.
@@ -63,6 +61,8 @@ jobs:
   check:
     name: Check
     uses: pharmaverse/admiralci/.github/workflows/r-cmd-check.yml@main
+    with:
+      error-on: warning # TODO: find a way to ignore specific notes
     if: github.event_name == 'pull_request'
   docs:
     name: Documentation

diff --git a/DESCRIPTION b/DESCRIPTION
@@ -1,7 +1,7 @@
 Package: pharmaversesdtm
 Type: Package
 Title: Test Data for the Pharmaverse Family of Packages
-Version: 0.1.1
+Version: 0.1.1.9000
 Authors@R: c(
   person("Edoardo", "Mancini", email = "edoardo.mancini@roche.com", role = c("aut", "cre")),
   person("Gayatri", "G", role = "aut"),

diff --git a/NEWS.md b/NEWS.md
@@ -1,3 +1,20 @@
+# pharmaversesdtm (development version)
+
+## New Features
+
+Following Vaccine Specific SDTM datasets have been added. (#4)
+
+ - `ce_vaccine`
+ - `dm_vaccine`
+ - `ex_vaccine`
+ - `face_vaccine`
+ - `is_vaccine`
+ - `vs_vaccine`
+ - `suppce_vaccine`
+ - `suppdm_vaccine`
+ - `suppex_vaccine`
+ - `suppface_vaccine`
+
 # pharmaversesdtm 0.1.1
 
 ## Documentation

diff --git a/R/data.R b/R/data.R
@@ -214,3 +214,80 @@
 #'
 #' @source \url{https://github.com/cdisc-org/sdtm-adam-pilot-project/blob/master/updated-pilot-submission-package/900172/m5/datasets/cdiscpilot01/tabulations/sdtm/sv.xpt?raw=true} # nolint
 "sv"
+
+#' Demographics Dataset for Vaccine Studies
+#'
+#' An example SDTM DM dataset for vaccine studies
+#'
+#' @source \url{https://github.com/pharmaverse/admiralvaccine/blob/main/data/vx_dm.rda} # nolint
+"dm_vaccine"
+
+#' Vital Signs Dataset for Vaccine Studies
+#'
+#' An example SDTM VS dataset for vaccine studies
+#'
+#' @source \url{https://github.com/pharmaverse/admiralvaccine/blob/main/data/vx_vs.rda} # nolint
+"vs_vaccine"
+
+#' Clinical Events Dataset for Vaccine Studies
+#'
+#' An example SDTM CE dataset for vaccine studies
+#'
+#' @source \url{https://github.com/pharmaverse/admiralvaccine/blob/main/data/vx_ce.rda} # nolint
+"ce_vaccine"
+
+#' Exposures Dataset for Vaccine Studies
+#'
+#' An example SDTM EX dataset for vaccine studies
+#'
+#' @source \url{https://github.com/pharmaverse/admiralvaccine/blob/main/data/vx_ex.rda} # nolint
+"ex_vaccine"
+
+#' Immunogenicity Specimen Assessments Dataset for Vaccine Studies
+#'
+#' An example SDTM IS dataset for vaccine studies
+#'
+#' @source \url{https://github.com/pharmaverse/admiralvaccine/blob/main/data/vx_is.rda} # nolint
+"is_vaccine"
+
+#' Findings About Clinical Events Dataset for Vaccine Studies
+#'
+#' An example SDTM FACE dataset for vaccine studies
+#'
+#' @source \url{https://github.com/pharmaverse/admiralvaccine/blob/main/data/vx_face.rda} # nolint
+"face_vaccine"
+
+#' Supplemental Qualifiers for Clinical Events Dataset for Vaccine Studies
+#'
+#' An example SDTM SUPPCE dataset for vaccine studies
+#'
+#' @source \url{https://github.com/pharmaverse/admiralvaccine/blob/main/data/vx_suppce.rda} # nolint
+"suppce_vaccine"
+
+#' Supplemental Qualifiers for Demographics Dataset for Vaccine Studies
+#'
+#' An example SDTM SUPPDM dataset for vaccine studies
+#'
+#' @source \url{https://github.com/pharmaverse/admiralvaccine/blob/main/data/vx_suppdm.rda} # nolint
+"suppdm_vaccine"
+
+#' Supplemental Qualifiers for Exposures Dataset for Vaccine Studies
+#'
+#' An example SDTM SUPPEX dataset for vaccine studies
+#'
+#' @source \url{https://github.com/pharmaverse/admiralvaccine/blob/main/data/vx_suppex.rda} # nolint
+"suppex_vaccine"
+
+#' Supplemental Qualifiers for Findings About for Clinical Events Dataset for Vaccine Studies # nolint
+#'
+#' An example SDTM SUPPFACE dataset for vaccine studies
+#'
+#' @source \url{https://github.com/pharmaverse/admiralvaccine/blob/main/data/vx_suppface.rda} # nolint
+"suppface_vaccine"
+
+#' Supplemental Qualifiers for Immunogenicity Specimen Assessments Dataset for Vaccine Studies # nolint
+#'
+#' An example SDTM SUPPIS dataset for vaccine studies
+#'
+#' @source \url{https://github.com/pharmaverse/admiralvaccine/blob/main/data/vx_suppis.rda} # nolint
+"suppis_vaccine"
diff --git a/data-raw/ce_vaccine.R b/data-raw/ce_vaccine.R
@@ -0,0 +1,219 @@
+# Dataset: ce_vaccine
+# Description: CE test SDTM dataset for Vaccine studies
+
+
+# Load libraries ----
+
+library(tibble)
+library(dplyr)
+library(tidyr)
+library(metatools)
+
+# Create CE
+
+## Create a dummy CE dataset
+
+ce_t <- tribble(
+  ~STUDYID, ~DOMAIN, ~USUBJID, ~CESEQ, ~CETERM, ~CEDECOD, ~CELAT, ~CELOC, ~CEPRESP, ~CEOCCUR,
+  ~CESEV, ~CEREL, ~CEOUT, ~EPOCH, ~CEDTC, ~CESTDTC, ~CEENDTC, ~CEDUR, ~CETPTREF, ~CERFTDTC,
+  ~CEEVINTX, ~CESTAT, ~CEREASND,
+  "ABC", "CE", "ABC-1001", 1, "CHILLS", "Chills", NA,
+  NA, "Y", "N", NA, NA, NA, NA,
+  NA, NA, NA, NA, "VACCINATION 1", "2021-11-03T10:50:00",
+  "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1001", 2, "PAIN AT INJECTION SITE", "Injection site pain",
+  "LEFT", "DELTOID MUSCLE", "Y", "Y", "MODERATE", "RELATED", "RECOVERED/RESOLVED",
+  "VACCINATION 1", "2021-11-09", "2021-11-04", "2021-11-07", "P4D", "VACCINATION 1",
+  "2021-11-03T10:50:00", "SINCE VACCINATION", NA,
+  NA,
+  "ABC", "CE", "ABC-1001", 3, "REDNESS", "Erythema", "LEFT",
+  "DELTOID MUSCLE", "Y", "Y", "MODERATE", "RELATED", "RECOVERED/RESOLVED",
+  "VACCINATION 1", "2021-11-06", "2021-11-04", "2021-11-04", "P1D", "VACCINATION 1",
+  "2021-11-03T10:50:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1001", 4, "SWELLING", "Swelling",
+  "LEFT", "DELTOID MUSCLE", "Y", "Y", "MODERATE", "RELATED", "RECOVERED/RESOLVED",
+  "VACCINATION 1", "2021-11-11", "2021-11-03", "2021-11-09", "P7D", "VACCINATION 1",
+  "2021-11-03T10:50:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1001", 5, "DIARRHEA", "Diarrhoea", NA,
+  NA, "Y", "N", NA, NA, NA, NA,
+  NA, NA, NA, NA, "VACCINATION 1", "2021-11-03T10:50:00",
+  "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1001", 6, "FATIGUE", "Fatigue", NA,
+  NA, "Y", "Y", "MILD", "RELATED", "RECOVERED/RESOLVED", "VACCINATION 1",
+  "2021-11-06", "2021-11-03", "2021-11-04", "P2D", "VACCINATION 1",
+  "2021-11-03T10:50:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1001", 7, "FEVER", "Pyrexia", NA,
+  NA, "Y", "N", NA, NA, NA, NA,
+  NA, NA, NA, NA, "VACCINATION 1", "2021-11-03T10:50:00",
+  "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1001", 8, "HEADACHE", "Headache", NA,
+  NA, "Y", "N", NA, NA, NA, NA,
+  NA, NA, NA, NA, "VACCINATION 1", "2021-11-03T10:50:00",
+  "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1001", 9, "NEW OR WORSENED JOINT PAIN",
+  "Arthralgia", NA, NA, "Y", "Y", "MILD", "RELATED",
+  "RECOVERED/RESOLVED", "VACCINATION 1", "2021-11-06", "2021-11-04", "2021-11-04",
+  "P1D", "VACCINATION 1", "2021-11-03T10:50:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1001", 10, "NEW OR WORSENED MUSCLE PAIN",
+  "Myalgia", NA, NA, "Y", "Y", "MILD", "RELATED",
+  "RECOVERED/RESOLVED", "VACCINATION 1", "2021-11-06", "2021-11-04", "2021-11-04",
+  "P1D", "VACCINATION 1", "2021-11-03T10:50:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1001", 11, "VOMITING", "Vomiting", NA,
+  NA, "Y", "N", NA, NA, NA, NA,
+  NA, NA, NA, NA, "VACCINATION 1", "2021-11-03T10:50:00",
+  "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1001", 12, "CHILLS", "Chills", NA, NA,
+  "Y", NA, NA, NA, NA, NA,
+  NA, NA, NA, NA, "VACCINATION 2", "2021-12-30T09:10:00",
+  "SINCE VACCINATION", "NOT DONE", "SUBJECT DID NOT COMPLETE ELECTRONIC DIARY",
+  "ABC", "CE", "ABC-1001", 13, "PAIN AT INJECTION SITE", "Injection site pain",
+  "LEFT", "DELTOID MUSCLE", "Y", NA, NA, NA,
+  NA, NA, NA, NA, NA, NA,
+  "VACCINATION 2", "2021-12-30T09:10:00", "SINCE VACCINATION", "NOT DONE",
+  "SUBJECT DID NOT COMPLETE ELECTRONIC DIARY",
+  "ABC", "CE", "ABC-1001", 14, "REDNESS", "Erythema", "LEFT",
+  "DELTOID MUSCLE", "Y", NA, NA, NA, NA,
+  NA, NA, NA, NA, NA, "VACCINATION 2",
+  "2021-12-30T09:10:00", "SINCE VACCINATION", "NOT DONE",
+  "SUBJECT DID NOT COMPLETE ELECTRONIC DIARY",
+  "ABC", "CE", "ABC-1001", 15, "SWELLING", "Swelling", "LEFT",
+  "DELTOID MUSCLE", "Y", NA, NA, NA, NA,
+  NA, NA, NA, NA, NA, "VACCINATION 2",
+  "2021-12-30T09:10:00", "SINCE VACCINATION", "NOT DONE",
+  "SUBJECT DID NOT COMPLETE ELECTRONIC DIARY",
+  "ABC", "CE", "ABC-1001", 16, "DIARRHEA", "Diarrhoea", NA,
+  NA, "Y", NA, NA, NA, NA, NA,
+  NA, NA, NA, NA, "VACCINATION 2", "2021-12-30T09:10:00",
+  "SINCE VACCINATION", "NOT DONE", "SUBJECT DID NOT COMPLETE ELECTRONIC DIARY",
+  "ABC", "CE", "ABC-1001", 17, "FATIGUE", "Fatigue", NA,
+  NA, "Y", NA, NA, NA, NA, NA,
+  NA, NA, NA, NA, "VACCINATION 2", "2021-12-30T09:10:00",
+  "SINCE VACCINATION", "NOT DONE", "SUBJECT DID NOT COMPLETE ELECTRONIC DIARY",
+  "ABC", "CE", "ABC-1001", 18, "FEVER", "Pyrexia", NA,
+  NA, "Y", NA, NA, NA, NA, NA,
+  NA, NA, NA, NA, "VACCINATION 2", "2021-12-30T09:10:00",
+  "SINCE VACCINATION", "NOT DONE", "SUBJECT DID NOT COMPLETE ELECTRONIC DIARY",
+  "ABC", "CE", "ABC-1001", 19, "HEADACHE", "Headache", NA, NA, "Y", NA, NA, NA, NA, NA, NA, NA, NA,
+  NA, "VACCINATION 2", "2021-12-30T09:10:00", "SINCE VACCINATION", "NOT DONE",
+  "SUBJECT DID NOT COMPLETE ELECTRONIC DIARY",
+  "ABC", "CE", "ABC-1001", 20, "NEW OR WORSENED JOINT PAIN", "Arthralgia", NA, NA, "Y", NA, NA, NA,
+  NA, NA, NA, NA, NA, NA, "VACCINATION 2", "2021-12-30T09:10:00", "SINCE VACCINATION", "NOT DONE",
+  "SUBJECT DID NOT COMPLETE ELECTRONIC DIARY",
+  "ABC", "CE", "ABC-1001", 21, "NEW OR WORSENED MUSCLE PAIN", "Myalgia", NA, NA, "Y", NA, NA, NA,
+  NA, NA, NA, NA, NA, NA, "VACCINATION 2", "2021-12-30T09:10:00", "SINCE VACCINATION", "NOT DONE",
+  "SUBJECT DID NOT COMPLETE ELECTRONIC DIARY",
+  "ABC", "CE", "ABC-1001", 22, "VOMITING", "Vomiting", NA, NA, "Y", NA, NA, NA, NA, NA, NA, NA, NA,
+  NA, "VACCINATION 2", "2021-12-30T09:10:00", "SINCE VACCINATION", "NOT DONE",
+  "SUBJECT DID NOT COMPLETE ELECTRONIC DIARY",
+  "ABC", "CE", "ABC-1002", 1, "CHILLS", "Chills", NA, NA, "Y", "N", NA, NA, NA, NA, NA, NA, NA, NA,
+  "VACCINATION 1", "2021-10-07T12:48:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 2, "PAIN AT INJECTION SITE", "Injection site pain", "LEFT",
+  "DELTOID MUSCLE", "Y", "N", NA, NA, NA, NA, NA, NA, NA, NA, "VACCINATION 1",
+  "2021-10-07T12:48:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 3, "REDNESS", "Erythema", "LEFT", "DELTOID MUSCLE",
+  "Y", "Y", "MILD", "RELATED", "RECOVERED/RESOLVED", "VACCINATION 1", "2021-10-11", "2021-10-09",
+  "2021-10-09", "P1D", "VACCINATION 1", "2021-10-07T12:48:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 4, "SWELLING", "Swelling", "LEFT", "DELTOID MUSCLE", "Y", "N", NA,
+  NA, NA, NA, NA, NA, NA, NA, "VACCINATION 1", "2021-10-07T12:48:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 5, "DIARRHEA", "Diarrhoea", NA, NA, "Y", "N", NA, NA, NA, NA, NA, NA, NA,
+  NA, "VACCINATION 1", "2021-10-07T12:48:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 6, "FATIGUE", "Fatigue", NA, NA, "Y", "N", NA, NA, NA, NA, NA, NA, NA,
+  NA, "VACCINATION 1", "2021-10-07T12:48:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 7, "FEVER", "Pyrexia", NA, NA, "Y", "N", NA, NA, NA, NA, NA, NA, NA, NA,
+  "VACCINATION 1", "2021-10-07T12:48:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 8, "HEADACHE", "Headache", NA, NA, "Y", "Y", "MODERATE", "RELATED",
+  "RECOVERED/RESOLVED", "VACCINATION 1", "2021-10-13", "2021-10-11", "2021-10-11", "P1D",
+  "VACCINATION 1", "2021-10-07T12:48:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 9, "NEW OR WORSENED JOINT PAIN", "Arthralgia", NA, NA, "Y", "N", NA, NA,
+  NA, NA, NA, NA, NA, NA, "VACCINATION 1", "2021-10-07T12:48:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 10, "NEW OR WORSENED MUSCLE PAIN", "Myalgia", NA, NA, "Y", "N", NA, NA,
+  NA, NA, NA, NA, NA, NA, "VACCINATION 1", "2021-10-07T12:48:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 11, "VOMITING", "Vomiting", NA, NA, "Y", "N", NA, NA, NA, NA, NA, NA, NA,
+  NA, "VACCINATION 1", "2021-10-07T12:48:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 12, "CHILLS", "Chills", NA, NA, "Y", "N", NA, NA, NA, NA, NA, NA, NA, NA,
+  "VACCINATION 2", "2021-12-16T12:41:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 13, "PAIN AT INJECTION SITE", "Injection site pain", "LEFT",
+  "DELTOID MUSCLE", "Y", "Y", "MILD", "RELATED", "RECOVERED/RESOLVED", "VACCINATION 2",
+  "2021-12-21", "2021-12-16", "2021-12-19", "P4D", "VACCINATION 2", "2021-12-16T12:41:00",
+  "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 14, "REDNESS", "Erythema", "LEFT", "DELTOID MUSCLE", "Y", "Y", "MILD",
+  "RELATED", "RECOVERED/RESOLVED", "VACCINATION 2", "2021-12-23", "2021-12-17", "2021-12-21", "P5D",
+  "VACCINATION 2", "2021-12-16T12:41:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 15, "SWELLING", "Swelling", "LEFT", "DELTOID MUSCLE", "Y", "Y", "MILD",
+  "RELATED", "RECOVERED/RESOLVED", "VACCINATION 2", "2021-12-21", "2021-12-17", "2021-12-19", "P3D",
+  "VACCINATION 2", "2021-12-16T12:41:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 16L, "DIARRHEA", "Diarrhoea", NA, NA, "Y", "N", NA, NA, NA, NA, NA, NA,
+  NA, NA, "VACCINATION 2", "2021-12-16T12:41:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 17L, "FATIGUE", "Fatigue", NA, NA, "Y", "N", NA, NA, NA, NA, NA, NA, NA,
+  NA, "VACCINATION 2", "2021-12-16T12:41:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 18L, "FEVER", "Pyrexia", NA, NA, "Y", "N", NA, NA, NA, NA, NA, NA, NA,
+  NA, "VACCINATION 2", "2021-12-16T12:41:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 19L, "HEADACHE", "Headache", NA, NA, "Y", "Y", "MILD", "RELATED",
+  "RECOVERED/RESOLVED", "VACCINATION 2", "2021-12-23", "2021-12-21", "2021-12-21", "P1D",
+  "VACCINATION 2", "2021-12-16T12:41:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 20L, "NEW OR WORSENED JOINT PAIN", "Arthralgia", NA, NA, "Y", "N", NA,
+  NA, NA, NA, NA, NA, NA, NA, "VACCINATION 2", "2021-12-16T12:41:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 21L, "NEW OR WORSENED MUSCLE PAIN", "Myalgia", NA, NA, "Y", "N", NA, NA,
+  NA, NA, NA, NA, NA, NA, "VACCINATION 2", "2021-12-16T12:41:00", "SINCE VACCINATION", NA, NA,
+  "ABC", "CE", "ABC-1002", 22L, "VOMITING", "Vomiting", NA, NA, "Y", "N", NA, NA, NA, NA, NA, NA,
+  NA, NA, "VACCINATION 2", "2021-12-16T12:41:00", "SINCE VACCINATION", NA, NA
+)
+
+## Create final CE dataset ----
+
+vx_ce <- ce_t %>%
+  mutate(
+    CELNKGRP = paste(CETPTREF, "-", CETERM),
+    CECAT = "REACTOGENICITY",
+    CESCAT = ifelse(is.na(CELAT), "SYSTEMIC", "ADMINISTRATION SITE"),
+    CETPT = "DAY 7",
+    CETPTNUM = 7
+  ) %>%
+  unite(
+    CELNKID, CETPTREF, CELOC, CELAT, CETERM,
+    sep = "-", na.rm = TRUE, remove = FALSE
+  ) %>%
+  select(
+    STUDYID, DOMAIN, USUBJID, CESEQ, CELNKID, CELNKGRP, CETERM,
+    CEDECOD, CELAT, CELOC, CECAT, CESCAT, CEPRESP, CEOCCUR, CESEV, CEREL,
+    CEOUT, EPOCH, CEDTC, CESTDTC, CEENDTC, CEDUR, CETPT, CETPTNUM, CETPTREF,
+    CERFTDTC, CEEVINTX, CESTAT, CEREASND
+  )
+
+ce_vaccine <- vx_ce %>% add_labels(
+  STUDYID = "Study Identifier",
+  DOMAIN = "Domain Abbreviation",
+  USUBJID = "Unique Subject Identifier",
+  CESEQ = "Sequence Number",
+  CELNKID = "Link ID",
+  CELNKGRP = "Link Group ID",
+  CETERM = "Reported Term for the Clinical Event",
+  CEDECOD = "Dictionary-Derived Term",
+  CELAT = "Laterality of Location of Clinical Event",
+  CELOC = "Location of Clinical Event",
+  CECAT = "Category for Clinical Event",
+  CESCAT = "Subcategory for Clinical Event",
+  CEPRESP = "Clinical Event Pre-Specified",
+  CEOCCUR = "Clinical Event Occurrence",
+  CESEV = "Severity/Intensity",
+  CEREL = "Causality",
+  CEOUT = "Outcome of Clinical Event",
+  EPOCH = "Epoch",
+  CEDTC = "Date/Time of Event Collection",
+  CESTDTC = "Start Date/Time of Clinical Event",
+  CEENDTC = "End Date/Time of Clinical Event",
+  CEDUR = "Duration of Clinical Event",
+  CETPT = "Planned Time Point Name",
+  CETPTNUM = "Planned Time Point Number",
+  CETPTREF = "Time Point Reference",
+  CERFTDTC = "Date/Time of Reference Time Point",
+  CEEVINTX = "Evaluation Interval Text",
+  CESTAT = "Completion Status",
+  CEREASND = "Reason Clinical Event Not Collected"
+)
+
+# Label CE dataset ----
+attr(ce_vaccine, "label") <- "Clinical Events"
+
+# Save dataset ----
+usethis::use_data(ce_vaccine, overwrite = TRUE)