diff --git a/.github/workflows/ci-test.yml b/.github/workflows/ci-test.yml
index e4fce82b..5d4ba447 100644
--- a/.github/workflows/ci-test.yml
+++ b/.github/workflows/ci-test.yml
@@ -6,36 +6,42 @@ jobs:
       fail-fast: false
       max-parallel: 1
       matrix:
-        python_version: ['2.7', '3.4.10', '3.5', '3.6', '3.7', '3.8', '3.9']
+        python_version: ['2.7', '3.4', '3.5', '3.6', '3.7', '3.8', '3.9']
     runs-on: ubuntu-20.04
     steps:
       - name: Checkout repo
         uses: actions/checkout@v2
         with:
           ref: ${{ github.ref }}
-      - name: Setup python
-        if: ${{ matrix.python_version != '3.4.10' }}
-        uses: actions/setup-python@v2
+      - name: Setup miniconda
+        uses: conda-incubator/setup-miniconda@v2
         with:
+          auto-update-conda: true
+          channels: conda-forge
           python-version: ${{ matrix.python_version }}
-          architecture: x64
-      - name: Setup python manually
-        if: ${{ matrix.python_version == '3.4.10' }}
+          activate-environment: qiniu-sdk
+          auto-activate-base: false
+      - name: Setup pip
+        shell: bash -l {0}
         env:
-          PYTHON_SOURCE_URL: https://www.python.org/ftp/python/${{ matrix.python_version }}/Python-${{ matrix.python_version }}.tgz
+          PYTHON_VERSION: ${{ matrix.python_version }}
+          PIP_BOOTSTRAP_SCRIPT_PREFIX: https://bootstrap.pypa.io/pip
         run: |
-          cd /tmp
-          curl -s -L "$PYTHON_SOURCE_URL" | tar -zxf - -C ./
-          cd Python-${{ matrix.python_version }}
-          ./configure --enable-optimizations
-          make
-          sudo make install
-          echo 'export PATH="/opt/python/bin:$PATH"' >> $HOME/.bashrc
+          MAJOR=$(echo "$PYTHON_VERSION" | cut -d'.' -f1)
+          MINOR=$(echo "$PYTHON_VERSION" | cut -d'.' -f2)
+          # reinstall pip by some python(<3.7) not compatible
+          if ! [[ $MAJOR -ge 3 && $MINOR -ge 7 ]]; then
+            cd /tmp
+            wget -qLO get-pip.py "$PIP_BOOTSTRAP_SCRIPT_PREFIX/$MAJOR.$MINOR/get-pip.py"
+            python get-pip.py --user
+          fi
       - name: Install dependencies
+        shell: bash -l {0}
         run: |
           python -m pip install --upgrade pip
-          pip install "coverage<7.2" flake8 pytest pytest-cov freezegun requests scrutinizer-ocular codecov
+          python -m pip install --ignore-installed "coverage<7.2" flake8 pytest pytest-cov freezegun requests scrutinizer-ocular codecov
       - name: Run cases
+        shell: bash -l {0}
         env:
           QINIU_ACCESS_KEY: ${{ secrets.QINIU_ACCESS_KEY }}
           QINIU_SECRET_KEY: ${{ secrets.QINIU_SECRET_KEY }}
diff --git a/qiniu/config.py b/qiniu/config.py
index 6d72702f..cb2ac57c 100644
--- a/qiniu/config.py
+++ b/qiniu/config.py
@@ -5,6 +5,7 @@
 RSF_HOST = 'http://rsf.qbox.me'  # 列举操作Host
 API_HOST = 'http://api.qiniuapi.com'  # 数据处理操作Host
 UC_HOST = region.UC_HOST  # 获取空间信息Host
+QUERY_REGION_HOST = 'https://kodo-config.qiniuapi.com'
 
 _BLOCK_SIZE = 1024 * 1024 * 4  # 断点续传分块大小，该参数为接口规格，暂不支持修改
 
@@ -14,11 +15,12 @@
     'default_rsf_host': RSF_HOST,
     'default_api_host': API_HOST,
     'default_uc_host': UC_HOST,
-    'default_uc_backup_hosts': [
-        'kodo-config.qiniuapi.com',
+    'default_query_region_host': QUERY_REGION_HOST,
+    'default_query_region_backup_hosts': [
+        'uc.qbox.me',
         'api.qiniu.com'
     ],
-    'default_uc_backup_retry_times': 2,
+    'default_backup_hosts_retry_times': 2,
     'connection_timeout': 30,  # 链接超时为时间为30s
     'connection_retries': 3,  # 链接重试次数为3次
     'connection_pool': 10,  # 链接池个数为10
@@ -31,8 +33,9 @@
     'default_rsf_host': False,
     'default_api_host': False,
     'default_uc_host': False,
-    'default_uc_backup_hosts': False,
-    'default_uc_backup_retry_times': False,
+    'default_query_region_host': False,
+    'default_query_region_backup_hosts': False,
+    'default_backup_hosts_retry_times': False,
     'connection_timeout': False,
     'connection_retries': False,
     'connection_pool': False,
@@ -52,7 +55,8 @@ def set_default(
         default_zone=None, connection_retries=None, connection_pool=None,
         connection_timeout=None, default_rs_host=None, default_uc_host=None,
         default_rsf_host=None, default_api_host=None, default_upload_threshold=None,
-        default_uc_backup_hosts=None, default_uc_backup_retry_times=None):
+        default_query_region_host=None, default_query_region_backup_hosts=None,
+        default_backup_hosts_retry_times=None):
     if default_zone:
         _config['default_zone'] = default_zone
         _is_customized_default['default_zone'] = True
@@ -68,14 +72,21 @@ def set_default(
     if default_uc_host:
         _config['default_uc_host'] = default_uc_host
         _is_customized_default['default_uc_host'] = True
-        _config['default_uc_backup_hosts'] = []
-        _is_customized_default['default_uc_backup_hosts'] = True
-    if default_uc_backup_hosts:
-        _config['default_uc_backup_hosts'] = default_uc_backup_hosts
-        _is_customized_default['default_uc_backup_hosts'] = True
-    if default_uc_backup_retry_times:
-        _config['default_uc_backup_retry_times'] = default_uc_backup_retry_times
-        _is_customized_default['default_uc_backup_retry_times'] = True
+        _config['default_query_region_host'] = default_uc_host
+        _is_customized_default['default_query_region_host'] = True
+        _config['default_query_region_backup_hosts'] = []
+        _is_customized_default['default_query_region_backup_hosts'] = True
+    if default_query_region_host:
+        _config['default_query_region_host'] = default_query_region_host
+        _is_customized_default['default_query_region_host'] = True
+        _config['default_query_region_backup_hosts'] = []
+        _is_customized_default['default_query_region_backup_hosts'] = True
+    if default_query_region_backup_hosts:
+        _config['default_query_region_backup_hosts'] = default_query_region_backup_hosts
+        _is_customized_default['default_query_region_backup_hosts'] = True
+    if default_backup_hosts_retry_times:
+        _config['default_backup_hosts_retry_times'] = default_backup_hosts_retry_times
+        _is_customized_default['default_backup_hosts_retry_times'] = True
     if connection_retries:
         _config['connection_retries'] = connection_retries
         _is_customized_default['connection_retries'] = True
diff --git a/qiniu/http/client.py b/qiniu/http/client.py
index 8dfa2369..97c41980 100644
--- a/qiniu/http/client.py
+++ b/qiniu/http/client.py
@@ -66,7 +66,7 @@ def send_request(self, request, middlewares=None, **kwargs):
             return None, ResponseInfo(None, e)
 
         # if ok try dump response info to dict from json
-        if not resp_info.ok:
+        if not resp_info.ok():
             return None, resp_info
 
         try:
diff --git a/qiniu/region.py b/qiniu/region.py
index 1ffc5f46..acab5c4e 100644
--- a/qiniu/region.py
+++ b/qiniu/region.py
@@ -227,8 +227,8 @@ def bucket_hosts(self, ak, bucket):
         uc_host = UC_HOST
         if is_customized_default('default_uc_host'):
             uc_host = get_default('default_uc_host')
-        uc_backup_hosts = get_default('default_uc_backup_hosts')
-        uc_backup_retry_times = get_default('default_uc_backup_retry_times')
+        uc_backup_hosts = get_default('default_query_region_backup_hosts')
+        uc_backup_retry_times = get_default('default_backup_hosts_retry_times')
         url = "{0}/v4/query?ak={1}&bucket={2}".format(uc_host, ak, bucket)
 
         ret, _resp = qn_http_client.get(
diff --git a/test_qiniu.py b/test_qiniu.py
index 20962a94..151b861a 100644
--- a/test_qiniu.py
+++ b/test_qiniu.py
@@ -1000,6 +1000,24 @@ class RegionTestCase(unittest.TestCase):
     test_rs_host = 'test.region.compatible.config.rs'
     test_rsf_host = 'test.region.compatible.config.rsf'
 
+    @staticmethod
+    def restore_hosts():
+        set_default(
+            default_rs_host=qiniu.config.RS_HOST,
+            default_rsf_host=qiniu.config.RSF_HOST,
+            default_uc_host=qiniu.config.UC_HOST,
+            default_query_region_host=qiniu.config.QUERY_REGION_HOST,
+            default_query_region_backup_hosts=[
+                'uc.qbox.me',
+                'api.qiniu.com'
+            ]
+        )
+        qiniu.config._is_customized_default['default_rs_host'] = False
+        qiniu.config._is_customized_default['default_rsf_host'] = False
+        qiniu.config._is_customized_default['default_uc_host'] = False
+        qiniu.config._is_customized_default['default_query_region_host'] = False
+        qiniu.config._is_customized_default['default_query_region_backup_hosts'] = False
+
     def test_config_compatible(self):
         try:
             set_default(default_rs_host=self.test_rs_host)
@@ -1008,16 +1026,24 @@ def test_config_compatible(self):
             assert zone.get_rs_host("mock_ak", "mock_bucket") == self.test_rs_host
             assert zone.get_rsf_host("mock_ak", "mock_bucket") == self.test_rsf_host
         finally:
-            set_default(default_rs_host=qiniu.config.RS_HOST)
-            set_default(default_rsf_host=qiniu.config.RSF_HOST)
-            qiniu.config._is_customized_default['default_rs_host'] = False
-            qiniu.config._is_customized_default['default_rsf_host'] = False
+            RegionTestCase.restore_hosts()
+
+    def test_query_region_with_custom_domain(self):
+        try:
+            set_default(
+                default_query_region_host='https://fake-uc.phpsdk.qiniu.com'
+            )
+            zone = Zone()
+            data = zone.bucket_hosts(access_key, bucket_name)
+            assert data != 'null'
+        finally:
+            RegionTestCase.restore_hosts()
 
     def test_query_region_with_backup_domains(self):
         try:
             set_default(
-                default_uc_host='https://fake-uc.phpsdk.qiniu.com',
-                default_uc_backup_hosts=[
+                default_query_region_host='https://fake-uc.phpsdk.qiniu.com',
+                default_query_region_backup_hosts=[
                     'unavailable-uc.phpsdk.qiniu.com',
                     'uc.qbox.me'
                 ]
@@ -1026,13 +1052,22 @@ def test_query_region_with_backup_domains(self):
             data = zone.bucket_hosts(access_key, bucket_name)
             assert data != 'null'
         finally:
+            RegionTestCase.restore_hosts()
+
+    def test_query_region_with_uc_and_backup_domains(self):
+        try:
             set_default(
-                default_uc_host=qiniu.config.UC_HOST,
-                default_uc_backup_hosts=[
-                    'kodo-config.qiniuapi.com',
-                    'api.qiniu.com'
+                default_uc_host='https://fake-uc.phpsdk.qiniu.com',
+                default_query_region_backup_hosts=[
+                    'unavailable-uc.phpsdk.qiniu.com',
+                    'uc.qbox.me'
                 ]
             )
+            zone = Zone()
+            data = zone.bucket_hosts(access_key, bucket_name)
+            assert data != 'null'
+        finally:
+            RegionTestCase.restore_hosts()
 
 
 class ReadWithoutSeek(object):