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rgiessmann authored Nov 27, 2023
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## This idea in short
When a compound, which is unobservable by analytical means, decays/decomposes, one can still determine its decomposition rate by measuring an equilibrium involving this compound. Exemplarily, a two-substrate two-product equilibrium, in this case nucleoside phosphorolysis (nucleoside + phosphate = nucleobase + pentose-1-phosphate) can be used to determine the decomposition rate of one of the products (pentose-1-phosphate).

This idea is about generalizing the kinetic vs equilibrium effect, and demonstrating on which scales of equilibrium constants this process works. Related results are already published in https://doi.org/10.1002/cphc.202000901 .
On the theoretical side, this idea is about generalizing the kinetic vs equilibrium effect, and demonstrating on which scales of equilibrium constants this process works.

On the applied / wet-lab side, a result using this idea is already published (for ribose-1-phosphate) in https://doi.org/10.1002/cphc.202000901

A dataset to write a publication about (for 2'-deoxyribose-1-phosphate) is at: https://doi.org/10.5281/zenodo.3572070

## Sounds great, but...
You are interested in this topic? But the idea is gibberish and incomplete, or non-sense? Well, you're probably right!
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