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Fix typo
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flalom committed Dec 13, 2024
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## How do mutations appear?

- Mutations occur due to replication errors (1 nucleotide per ~10^4) but with reparation mechanisms (1 error per 10^9 10^10)
- Mutations occur due to replication errors (1 nucleotide per ~10^4) but with reparation mechanisms (1 error per 10^7 - 10^9)
- As a consequence of DNA damage (~70,000 nucleotide lesions or modifications per day)
- Exposure to mutagens such as UV, smoking increases the mutations' frequency
- Exposure to mutagens such as UV, smoking increases the mutations' frequency

::: {.fragment .fade-in}
![Example UV damage](https://knowgenetics.org/wp-content/uploads/2012/12/amanda1.png){#fig_uv_damage fig-caption="Germline vs somatic mutations" width="250" height="200"}
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