4. SPM Toolbox
The user-friendly SPM Matlab Toolbox fits to the usual SPM-style analysis. The Toolbox, after specifying the SPM.mat file of your analysis, executes pTFCE enhancement on the selected statistical contrast and creates a new contrast for the enhanced image which can then be easily visualised and thresholded e.g. by using the 'Results' function of SPM.
Make sure you have Matlab and SPM installed (the toolbox is tested only with SPM12).
Please refer to the SPM homepage for installation instructions.
The pTFCE SPM Toolbox currently relies on the statistics and image processing Matlab toolboxes. A future release will get rid of these dependencies and rely only on SPM.
Download the latest version of the pTFCE SPM Toolbox here.
Unzip the downloaded file and copy its subfolder named 'pTFCE' into the 'toolbox' folder of your SPM installation.
Make sure the folder is added to your Matlab path.
With any installation issues, contact the developers.
Start pTFCE SPM Toolbox from the SPM "Toolboxes" roll-down menu.
Select the SPM.mat of your previously estimated analysis.
Select the contrast you want to enhance with pTFCE.
The pTFCE SPM Toolbox will create a new contrast item having the same contrast weights as the original contrast but enhances the statistical parametric map.
The probabilistic threshold-free cluster enhancement is performed in about 30-60 seconds.
See link for details.
Visualise the enhanced contrast (ending with pTFCE) with the "Results" button in SPM, as usual.
IMPORTANT NOTE: Since the pTFCE enhanced image integrates cluster information into the voxel-level, the table of cluster-level statistics generated by SPM do not apply after pTFCE correction. The peak-level statistics are still valid (and incorporate clustering information). The local maxima throughout the unthresholded image remain intact, and the number of significant local maxima usually increases (also note that SPM report only the 3 maxima per cluster).
