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Unsupervised clustering of globus pallidus and striato-thalamic regions

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Unbalanced fronto-pallidal neurocircuit underlying set shifting in OCD Kim, T et al., 2022, Brain.

  • Functional connectivity-based parcellation of striatum, globus pallidus, and thalamus
  • Exploiting a unsupervised clustering method, we parceled the globus pallidus into external and internal subregions, which are key regions for the direct and indirect pathways in the cortico-striatal circuitry.

Atlas created using resting-state fMRI

  • the atlas images are available upon request to the Lead Contact (Prof. Jun Soo Kwon).
  • data from 105 patients with drug-free OCD and 99 healthy volunteers.
  • data acquisition from Dept of Psychiatry at Seoul National University Hospital (PI: Prof. Jun Soo Kwon).

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