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# Day 19: Medicine for Rudolph | ||
Rudolph the Red-Nosed Reindeer is sick! His nose isn't shining very brightly, and he needs medicine. | ||
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Red-Nosed Reindeer biology isn't similar to regular reindeer biology; Rudolph is going to need custom-made medicine. Unfortunately, Red-Nosed Reindeer chemistry isn't similar to regular reindeer chemistry, either. | ||
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The North Pole is equipped with a Red-Nosed Reindeer nuclear fusion/fission plant, capable of constructing any Red-Nosed Reindeer molecule you need. It works by starting with some input molecule and then doing a series of **replacements**, one per step, until it has the right molecule. | ||
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However, the machine has to be calibrated before it can be used. Calibration involves determining the number of molecules that can be generated in one step from a given starting point. | ||
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For example, imagine a simpler machine that supports only the following replacements: | ||
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``` | ||
H => HO | ||
H => OH | ||
O => HH | ||
``` | ||
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Given the replacements above and starting with `HOH`, the following molecules could be generated: | ||
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``` | ||
HOOH (via H => HO on the first H). | ||
HOHO (via H => HO on the second H). | ||
OHOH (via H => OH on the first H). | ||
HOOH (via H => OH on the second H). | ||
HHHH (via O => HH). | ||
``` | ||
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So, in the example above, there are `4` **distinct molecules** (not five, because `HOOH` appears twice) after one replacement from `HOH`. Santa's favorite molecule, `HOHOHO`, can become `7` distinct molecules (over nine replacements: six from `H`, and three from `O`). | ||
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The machine replaces without regard for the surrounding characters. For example, given the string `H2O`, the transition `H => OO` would result in `OO2O`. | ||
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Your puzzle input describes all of the possible replacements and, at the bottom, the medicine molecule for which you need to calibrate the machine. **How many distinct molecules can be created** after all the different ways you can do one replacement on the medicine molecule? | ||
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## Part Two | ||
Now that the machine is calibrated, you're ready to begin molecule fabrication. | ||
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Molecule fabrication always begins with just a single electron, `e`, and applying replacements one at a time, just like the ones during calibration. | ||
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For example, suppose you have the following replacements: | ||
``` | ||
e => H | ||
e => O | ||
H => HO | ||
H => OH | ||
O => HH | ||
``` | ||
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If you'd like to make `HOH`, you start with `e`, and then make the following replacements: | ||
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``` | ||
e => O to get O | ||
O => HH to get HH | ||
H => OH (on the second H) to get HOH | ||
``` | ||
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So, you could make `HOH` after **`3` steps**. Santa's favorite molecule, `HOHOHO`, can be made in **`6` steps**. | ||
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How long will it take to make the medicine? Given the available **replacements** and the **medicine molecule** in your puzzle input, what is the **fewest number of steps** to go from `e` to the medicine molecule? |
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export function* getMutations(molecule: string, sequence: string, replacement: string): Generator<string> { | ||
// Create a regex to find the sequence in the molecule. | ||
const regex = new RegExp(sequence, 'g'); | ||
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let match: RegExpExecArray | null; | ||
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// Process all the matches in the molecule for the current replacement. | ||
while ((match = regex.exec(molecule))) { | ||
// Get the part before the match and after the match. | ||
const moleculeStart = molecule.substring(0, match.index); | ||
const moleculeEnd = molecule.substring(match.index + sequence.length); | ||
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// Yield the mutation of the molecule with the replacement done. | ||
yield `${moleculeStart}${replacement}${moleculeEnd}`; | ||
} | ||
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return; | ||
} |
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export type MachineInput = { | ||
medicineMolecule: string; | ||
replacements: Replacement[]; | ||
}; | ||
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export type Replacement = { | ||
sequence: string; | ||
replacement: string; | ||
}; | ||
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/* ========================================================================== */ | ||
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export function parseInput(input: string): MachineInput { | ||
const lines = input.split('\n'); | ||
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// The last line is the medicine molecule, we need this. | ||
const medicineMolecule = lines.pop(); | ||
// Before the medicine molecule is an empty string, this can be discarded. | ||
lines.pop(); | ||
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const replacements = lines.map(line => { | ||
const [sequence, replacement] = line.split(' => '); | ||
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return { sequence, replacement }; | ||
}); | ||
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return { | ||
medicineMolecule, | ||
replacements | ||
}; | ||
}; |
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import { MachineInput, parseInput } from './helpers/parse-input.js'; | ||
import { getMutations } from './helpers/get-mutations.js'; | ||
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/* ========================================================================== */ | ||
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function countNumberOfMutations(machineInput: MachineInput): number { | ||
const mutations = new Set<string>(); | ||
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machineInput.replacements.forEach(({ replacement, sequence }) => { | ||
for (const mutation of getMutations(machineInput.medicineMolecule, sequence, replacement)) { | ||
mutations.add(mutation); | ||
} | ||
}); | ||
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return mutations.size; | ||
} | ||
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/* ========================================================================== */ | ||
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async function solver(input: string): Promise<number> { | ||
const machineInput = parseInput(input); | ||
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return countNumberOfMutations(machineInput); | ||
} | ||
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/* ========================================================================== */ | ||
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export default { | ||
prompt: 'Number of distinct molecules', | ||
solver | ||
} satisfies Solution; |
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import { parseInput } from './helpers/parse-input.js'; | ||
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/* ========================================================================== */ | ||
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/** | ||
* My first solution was to take the letter 'e' as start and basically keep | ||
* applying the replacements like in part 1 till the medicine molecule has been | ||
* created. I was afraid it would create too many paths to follow and this soon | ||
* turned out to be true. | ||
* | ||
* My second solution was to work backwards, start from the medicine molecule | ||
* and reverse the replacements till it yields 'e' as a result. This seemed like | ||
* a valid strategy except it would never get to 'e'. At some point it would | ||
* reach a molecule which no longer contained parts which could be replaced. | ||
* | ||
* The current solution is not my own, it is based on a solution / explanation | ||
* found on Reddit. It works like magic. | ||
* | ||
* @see {@link https://www.reddit.com/r/adventofcode/comments/3xflz8/comment/cy4h7ji/} | ||
*/ | ||
async function solver(input: string): Promise<number> { | ||
const { medicineMolecule } = parseInput(input); | ||
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// A symbol starts with a capital letter. | ||
const symbolCount = medicineMolecule.match(/[A-Z]/g).length; | ||
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// For each Rn is there is matching occurrence of Ar. When the number of | ||
// times Rn appears in the molecule is know, we also know the number of | ||
// times Ar should be present in the molecule. | ||
const rnCount = medicineMolecule.match(/Rn/g).length; | ||
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// Count then number of times the letter Y is present in the molecule. | ||
const yCount = medicineMolecule.match(/Y/g).length; | ||
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return (symbolCount - (rnCount * 2) - (2 * yCount)) - 1; | ||
} | ||
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/* ========================================================================== */ | ||
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export default { | ||
prompt: 'Minimum steps required to create medicine molecule', | ||
solver | ||
} satisfies Solution; |