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210 public repositories
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Exemplary Protein PBPK Models
Whole-body PBPK model of dapagliflozin
Updated
Apr 17, 2023
MATLAB
Modeling of published clinical itraconazole-pioglitazone-DDI studies for model evaluation
Whole-body PBPK model of Amikacin
Updated
Oct 14, 2021
MATLAB
Physiologically-Based Pharmacokinetic (PBPK) Modeling of Fentanyl in Adults and Pediatric Patients
Whole-body PBPK model of ethinylestradiol as CYP1A2 DDI perpetrator drug
Updated
Apr 29, 2022
MATLAB
Whole-body parent-metabolite PBPK model of Clopidogrel for CYP2B6, CYP2C8, CYP2C19, and CYP3A4 DDGI Predictions
Modeling of published clinical Clopidogrel-Bupropion-DDI studies for model evaluation
Whole-body PBPK model of gemfibrozil as CYP2C8 and OATP1B1 DDI perpetrator drug
Whole-body PBPK model of Irinotecan (CPT-11) & SN-38 determining tumor tissue kinetics of both parent drug & active metabolite.
Whole-body PBPK model of probenecid (OAT perpetrator drug)
Whole-body PBPK model of finerenone (KERENDIA).
Whole-body PBPK model of valproic acid including non-linear binding with albumin in adults, children and children with hypoalbuminemia.
Modeling of published clinical gemfibrozil-pioglitazone-DDI studies for model evaluation
Updated
Nov 28, 2019
MATLAB
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