diff --git a/.github/workflows/docker/buildwheel.sh b/.github/workflows/docker/buildwheel.sh
new file mode 100644
index 00000000..f29b6a0a
--- /dev/null
+++ b/.github/workflows/docker/buildwheel.sh
@@ -0,0 +1,17 @@
+#!/bin/bash
+DOCKER_DIR="$( cd "$( dirname "${BASH_SOURCE[0]}" )" && pwd )"
+source "$DOCKER_DIR/shared.env"
+
+set -e -x
+
+ARCH=`uname -p`
+echo "arch=$ARCH"
+
+
+for V in "${PYTHON_VERSIONS[@]}"; do
+    PYBIN=/opt/python/$V/bin
+    rm -rf build/       # Avoid lib build by narrow Python is used by wide python
+    $PYBIN/python setup.py bdist_wheel
+done
+
+rm dist/*.tar.gz
\ No newline at end of file
diff --git a/.github/workflows/docker/shared.env b/.github/workflows/docker/shared.env
new file mode 100644
index 00000000..68d95486
--- /dev/null
+++ b/.github/workflows/docker/shared.env
@@ -0,0 +1,6 @@
+PYTHON_VERSIONS=(
+    cp39-cp39
+    cp38-cp38
+    cp37-cp37m
+    cp36-cp36m
+)
diff --git a/.github/workflows/wheels.yml b/.github/workflows/wheels.yml
new file mode 100644
index 00000000..43c146a5
--- /dev/null
+++ b/.github/workflows/wheels.yml
@@ -0,0 +1,138 @@
+name: Build and test wheels
+
+on:
+  push:
+    branches:
+      - main
+      - test
+    tags:
+      - '*'
+  release:
+    types: [published]
+
+jobs:
+  manylinux:
+    runs-on: ubuntu-latest
+    steps:
+      - name: Checkout
+        uses: actions/checkout@v2
+        with:
+            submodules: true
+
+      - name: Set up Python 3.8
+        uses: actions/setup-python@v2
+        with:
+          python-version: 3.8
+
+      - name: Build sdist
+        shell: bash
+        run: |
+          python setup.py sdist
+
+      - name: Upload sdist
+        uses: actions/upload-artifact@v2
+        with:
+          name: sdist
+          path: dist
+
+      - name: Build wheels in docker
+        shell: bash
+        run: |
+          docker run --rm -v `pwd`:/project -w /project quay.io/pypa/manylinux2010_x86_64 bash .github/workflows/docker/buildwheel.sh
+
+      - name: Upload Wheels
+        uses: actions/upload-artifact@v2
+        with:
+          name: wheels
+          path: dist
+
+  OSX-test:
+    needs: ['manylinux']
+    runs-on: macos-latest
+    strategy:
+      matrix:
+        python: [3.6, 3.7, 3.8]
+    steps:
+      - name: Download wheels
+        uses: actions/download-artifact@v2
+        with:
+          name: wheels
+      - name: Set up Python ${{ matrix.python }}
+        uses: actions/setup-python@v2
+        with:
+          python-version: ${{ matrix.python }}
+      - name: Install wheel and test
+        run: |
+          python -VV
+          # Install the local wheel
+          pip install tsdate --only-binary tsdate -f .
+          python -c "import tsdate"
+
+  windows-test:
+    needs: ['manylinux']
+    runs-on: windows-latest
+    strategy:
+      matrix:
+        python: [3.6, 3.7, 3.8] #Not 3.9 here as no wheel for llvmlite
+        wordsize: [64]
+    steps:
+      - name: Download wheels
+        uses: actions/download-artifact@v2
+        with:
+          name: wheels
+      - name: Set up Python ${{ matrix.python }}
+        uses: actions/setup-python@v2
+        with:
+          python-version: ${{ matrix.python }}
+      - name: Install wheel and test
+        run: |
+          python -VV
+          pip install wheel
+          # Install the local wheel
+          pip install tsdate --only-binary tsdate -f .
+          python -c "import tsdate"
+
+  manylinux-test:
+    runs-on: ubuntu-latest
+    needs: ['manylinux']
+    strategy:
+      matrix:
+        python: [3.6, 3.7, 3.8] #Not 3.9 here as no wheel for llvmlite
+    steps:
+      - name: Download wheels
+        uses: actions/download-artifact@v2
+        with:
+          name: wheels
+      - name: Set up Python
+        uses: actions/setup-python@v2
+        with:
+          python-version: ${{ matrix.python }}
+      - name: Install wheel and test
+        run: |
+          python -VV
+          # Install the local wheel
+          pip install tsdate --only-binary tsdate -f .
+          python -c "import tsdate"
+
+
+  PyPI_Upload:
+    runs-on: ubuntu-latest
+    needs: ['windows-test', 'OSX-test', 'manylinux-test']
+    steps:
+      - name: Download all
+        uses: actions/download-artifact@v2
+      - name: Move to dist
+        run: |
+          mkdir dist
+          cp */*.{whl,gz} dist/.
+      - name: Publish distribution to Test PyPI
+        if: github.event_name == 'push' && startsWith(github.event.ref, 'refs/tags')
+        uses: pypa/gh-action-pypi-publish@master
+        with:
+          password: ${{ secrets.test_pypi_password }}
+          repository_url: https://test.pypi.org/legacy/
+      - name: Publish distribution to PRODUCTION PyPI
+        if: github.event_name == 'release'
+        uses: pypa/gh-action-pypi-publish@master
+        with:
+          password: ${{ secrets.pypi_password }}
diff --git a/README.md b/README.md
index 0d6e5f0a..e18853d0 100644
--- a/README.md
+++ b/README.md
@@ -11,4 +11,3 @@ The method is designed to operate on the output of [tsinfer](https://tsinfer.rea
 
 Please refer to the [documentation](https://tsdate.readthedocs.io/en/latest/) for information on installing and using the software.
 
-Note: This documentation is currently under development. Please wait to use ``tsdate`` in your published work until the release of our preprint.