DESCRIPTION

Package: MAnorm2
Type: Package
Title: Tools for Normalizing and Comparing ChIP-seq Samples
Version: 1.2.2
Authors@R: person("Shiqi", "Tu", email = "tushiqi@picb.ac.cn",
                  role = c("aut", "cre"),
                  comment = c(ORCID = "0000-0003-3534-5714"))
Description: Chromatin immunoprecipitation followed by high-throughput
    sequencing (ChIP-seq) is the premier technology for profiling genome-wide
    localization of chromatin-binding proteins, including transcription
    factors and histones with various modifications.
    This package provides a robust method for normalizing ChIP-seq
    signals across individual samples or groups of samples. It also designs
    a self-contained system of statistical models for calling differential
    ChIP-seq signals between two or more biological conditions as well as
    for calling hypervariable ChIP-seq signals across samples. Refer to
    Tu et al. (2021) <doi:10.1101/gr.262675.120> and
    Chen et al. (2022) <doi:10.1186/s13059-022-02627-9>
    for associated statistical details.
URL: https://github.com/tushiqi/MAnorm2
BugReports: https://github.com/tushiqi/MAnorm2/issues
License: GPL-3
Encoding: UTF-8
LazyData: true
Depends: R (>= 3.5.0)
Imports:
    stats,
    graphics,
    methods,
    locfit (>= 1.5.9),
    scales (>= 0.3.0),
    statmod (>= 1.4.34)
Suggests:
    gplots (>= 3.0.1),
    DescTools (>= 0.99.24),
    knitr,
    rmarkdown
Date: 2022-10-28
RoxygenNote: 7.1.1
VignetteBuilder: knitr