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OPRD1

This repository contains all code and scripts used to perform the analyses described in the paper "Mirror effect of delta opioid receptor mutations on human metabolic homeostasis".

The repository includes both bioinformatics and biostatistics analyses.

Note: the code has not been tested outside of its original environment and depends on data not publicly available.

Bioinformatics

The bioinformatics analysis was performed using the scripts in the bioinformatics directory.

RNAseq

The different analysis steps are listed in the Nextflow script bioinformatics/RnaSeqAnalysis.nf.

Nextflow version used is 20.04.1.5335, R version used is 3.6.3 (February, 2020) on Debian GNU/Linux 9 (stretch, x86_64).

Biostatistics

The statistical analyses were performed using the scripts in the biostatistics directory.
The directory biostatistics/utils contains additional scripts needed in the analyses.

The R version used is the 4.0.2 (June, 2020) on Debian GNU/Linux 9 (stretch, x86_64) available as a Docker image (umr1283/stat:R402).

Contact

For questions and other discussion, please contact the authors.