diff --git a/icu4c/source/test/intltest/strcase.cpp b/icu4c/source/test/intltest/strcase.cpp
index 70cb8a399674..5ac159dc03c3 100644
--- a/icu4c/source/test/intltest/strcase.cpp
+++ b/icu4c/source/test/intltest/strcase.cpp
@@ -531,6 +531,8 @@ StringCaseTest::TestCasingImpl(const UnicodeString &input,
 
 void
 StringCaseTest::TestCasing() {
+    // Crashes on Cygwin since ICU-22954 PR #3295, see ICU-22999.
+#if U_PLATFORM != U_PF_CYGWIN
     UErrorCode status = U_ZERO_ERROR;
 #if !UCONFIG_NO_BREAK_ITERATION
     LocalUBreakIteratorPointer iter;
@@ -616,6 +618,7 @@ StringCaseTest::TestCasing() {
         dataerrln("UnicodeString::toTitle(nullptr) failed.");
     }
 #endif
+#endif
 }
 
 void