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Bioconductor Release v3.13

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@zhengxwen zhengxwen released this 11 Jun 06:29
· 61 commits to master since this release

CHANGES IN VERSION 1.28.0

  • hlaPredict() returns the dosage of HLA alleles when type="response+dosage", and hlaPredict() returns the best guess and dosages by default
  • a new option "Pos+Allele" in hlaPredict(), hlaGenoCombine(), hlaGenoSwitchStrand(), hlaSNPID() and hlaCheckSNPs() for matching genotypes by positions, reference and alternative alleles; it is particularly useful when the training and test set are both matched to the same reference genome, e.g., 1000 Genomes Project
  • hlaGDS2Geno() supports SeqArray GDS files
  • a new option 'maf' in hlaAttrBagging() and hlaParallelAttrBagging()
  • 'pos.start' and 'pos.end' are replaced by 'pos.mid' in hlaFlankingSNP() and hlaGenoSubsetFlank()
  • new function hlaAlleleToVCF() for converting the imputed HLA classical alleles to a VCF file

CHANGES IN VERSION 1.26.1

  • the hlaAttrBagging object can be removed in garbage collection without calling hlaClose()
  • enable internal GPU API
  • improved multithreaded performance compared with v1.26.0

CHANGES IN VERSION 1.26.0

  • users can interrupt the model building in an interactive R session
  • remove hlaErrMsg() since it is never used
  • a new option 'nthread' in hlaAttrBagging() as a complement to hlaParallelAttrBagging()
  • kernel version 1.5: generates the same training model as v1.4, but 2-6x faster, by taking advantage of Intel AVX, AVX2 and AVX512 intrinsics
  • new function hlaSetKernelTarget() to automatically select the CPU target the algorithm is optimized for